The EAs work only if MetaTrader is open, so by extension your computer must be turned on for MetaTrader to execute and for the EA to place and monitor trades.
If you don't want to have your computer turned on permanently, you could purchase a VPS (Virtual Private Server) and install Windows and MetaTrader on it: you would then connect via Remote Desktop to the VPS in order to work on MetaTrader. Many providers offer VPS for a monthly fee, with the option of having a managed service or an unmanaged service; a managed service and the Windows license can raise the monthly cost quite a bit.
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