I ignore margin for the most part and focus more on the risk per trade.
Just make sure that your available equity (wiggle room after margin) is large enough to cover your stop loss, so you don't get a margin call. The higher the leverage the better, IMO, for the above reason. Less of your account is used for the margin leaving more left over for available equity.
People caution against high leverage because of the temptation to go in too heavy and blow your account. If you calculate your risk properly before a trade, margin shouldn't be an issue.
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