FX ticks over on a continuous 24 hour clock throughout the world. But the majority of the momentum & trade volume activity occurs when London is up & running. That equates to: approx 7.00am (2.00am EST) through until around 4.00pm (11.00am EST).
After that, the activity starts to dwindle noticeably. There will be occasions after London closes when New York will still run prices back & forth for a semi-decent return, but they’re few & far between.
If you're looking to execute your strategies for the best possible opportunities, then you'd really want to be focusing on the time periods mentioned above.
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