For those trading Trevor's G/U Breakout Strategy, the next "overnight" period, which begins in about 3 hours, will be interesting. Fifteen minutes after the beginning of the period, the FOMC Statement and the Fed Funds Rate will be released.
If the GBP/USD reacts strongly to these releases, then the next "overnight" period High, or Low (or both) could be established within the first 30 - 45 minutes of the period. Then, we will have to decide whether these High and Low prices are valid for the Breakout Strategy. There are no rules for this. It will be a judgment call for each of us to make.
We can compare notes on this in about 12 hours, after the dust has settled, and before we have to place our entry orders.
Here are the times for the "overnight" period, and for the FOMC/Fed Funds releases, in several time-zones: