I usually do day and swing trades but I can’t deny that trading 5-minute charts can be profitable. Even the popular 3 Ducks Trading System originally uses the 5m chart 
Every time I try to experiment with the 5M charts, I get my ass chewed. I stay away from it.
Hmm… sounds painful, think I’ll stay away in case of chewing
Market microstructure is a field of studies market operation. So order flow is important to observe. Note if you are on the wrong side of the order flow the time frame won’t matter. You can only get out or loose money.