How Long Will a Vaccine Really Take?

This NYT article is definitely worth a read.

Hint…it’s gonna take a long time…

The grim truth behind this rosy forecast is that a vaccine probably won’t arrive any time soon. Clinical trials almost never succeed. We’ve never released a coronavirus vaccine for humans before. Our record for developing an entirely new vaccine is at least four years — more time than the public or the economy can tolerate social-distancing orders.

Current Hope: Vaccine by August 2021

Typical Reality: Vaccine by May 2036

Despite the unprecedented push for a vaccine, researchers caution that less than 10 percent of drugs that enter clinical trials are ever approved by the Food and Drug Administration.

The potential Covid-19 vaccines now in the pipeline might be more likely to fail because of the swift march through the research phase, said Robert van Exan, a cell biologist who has worked in the vaccine industry for decades. He predicts we won’t see a vaccine approved until at least 2021 or 2022, and even then, “this is very optimistic and of relatively low probability.”

And yet, he said, this kind of fast-tracking is “worth the try — maybe we will get lucky.”

The race for coronavirus vaccines: a graphical guide

An excellent graphical guide to the race for a coronavirus vaccine.

Read the NYT article mentioned above alongside this simply excellent explainer, which explores how long it will really take to develop a vaccine.

TL;DR: Under normal circumstances 15 years or so. We’re aiming for 10 to 12 times faster.

SARS-CoV-2 vaccines: a variety of approaches

All vaccines aim to expose the body to an antigen that won’t cause disease, but will provoke an immune response that can block or kill the virus if a person becomes infected. There are at least eight types being tried against the coronavirus, and they rely on different viruses or viral parts.

image

Industry trials

More than 70% of the groups leading vaccine research efforts are from industrial or private firms. Clinical trials start with small safety studies in animals and people, followed by much larger trials to determine whether a vaccine generates an immune response. Researchers are accelerating these steps and hope to have a vaccine ready in 18 months.

image

1 Like