You have to look at the “all-in” cost of trading, and also consider your timeframe and trade frequency.
I don’t worry too much about 1-2 pips either way because I tend to trade longer-term and less frequently. A couple of pips makes virtually no difference in my performance. Likewise with a commission, if it’s small. More important to me is the trust I have in my broker and the access I have to the tools and information I need, plus the pairs I want to trade.
When day frequently and for smaller market moves, though, clearly the spread becomes a concern. You need to combine the spread with the commission (if any) to get a real read on the cost of trading with a particular broker/dealer.
The question of fixed vs variable spreads also depends on your trading style and method. If you are going to trade during times when the spreads could be widened out (for example, around major data releases for some brokers) then going with a fixed spread broker would suit you better, most likely.